Sample SCoP models

Following are some sample SCoP models that are not included in the standard set of examples that is distributed with SCoP. If you have a model you would like to see here, contact support@simresinc.com.

Ion Transport, Channels, Kinetics

• Single channel with random decay constant
• Random channel model
• Assembly of random channels
• Single site channel - ensemble
• Michaelis-Menten enzyme-substrate reaction
• Ebihara-Johnson model for sodium current (1980)

Cell Models

• DiFrancesco-Noble model for Purkinje cell (1985)
• Model of SA node cell (Demir et al, 1994)

Physiology, Biology

• Propagated Hodgkin-Huxley Action Potential
• Propagated Hodgkin-Huxley Action Potential with Extracellular Potentials
• Diffusion model (lumped)
• Indicator-dilution model of the circulation
• Lotka-Volterra predation model (Predator-Prey)

Pharmacology, Toxicology, PBPK

• Methyl Mercury in Rats
• One compartment model with repetitive dosing
• Two compartment model with repetitive dosing
• Styrene inhalation model

Mathematics, Physics, Programming

• Finite difference oscillator; swept constant
• Oscillator with Hopf bifurcation
• Poincare oscillator
• Vertical motion with gravity
• Monte-Carlo derivation of Pi
• Sine wave with lag (phase shift)
• Spring model with multiple SOLVE statements
• Algebraic equation with definite integral